Gut, GLP-1 & metabolic

• Stool form (Bristol)

  Bristol stool scale. Digestion, hydration, gut motility.

• Microbiome markers

  Indirect microbiome proxies from stool morphology, inflammatory markers, and metabolite signatures.

• Glucose (urine)

  Spillover above the renal threshold. Tracks glycaemic control and metabolic state.

• Weight & body comp

  Daily mass, fluid retention proxy, and trend signal for CHF, metabolic, and recovery.

• Breath VOCs

  Volatile organic compounds in exhaled air. Metabolic state and gut signal.

• Stool imaging & analysis

  Bowl-mounted imaging with on-device computer vision for stool morphology (Bristol scale), frequency, colour, and gross inflammation markers.

• Urinalysis test strip

  10-parameter reagent strip read at the seat. Captures pH, nitrites, leukocytes, glucose, blood, protein, ketones, urobilinogen, bilirubin, and specific gravity from each void.

• Urine spectroscopy (optical / SERS)

  Non-contact optical analysis of urine in the bowl or stream. Uses vis-NIR absorbance, fluorescence, and surface-enhanced Raman spectroscopy (SERS) to fingerprint analytes without consumables. Calibrates against the same biochemistry strips read by urinalysis.

• Load cell array

  Strain-gauge load cells in the floor mat and seat for weight, weight distribution, balance, gait timing, and sit-to-stand dynamics.

• Breath VOC sensor

  Metal-oxide and electrochemical arrays for volatile organic compounds in exhaled breath. Useful for ketones, gut metabolites, and infection signatures.

1. 01

   How might we turn the toilet into the first daily feedback loop for the GLP-1 era?

2. 02

   How might we detect IBD/IBS flares and microbiome drift from passive stool signal?

3. 03

   How might we build the long-arc nutrition and metabolic record primary care does not hold?

Work on this Issue