Domains · Performance · Issue

Biological-age biomarkers

Biological-age proxies from urine, behaviour, and motion, without monthly bloodwork.

Also touches: Aging in Place
Biomarkers

  • Heart-rate variability

    Beat-to-beat variation. Autonomic balance, recovery, stress, and overtraining signal.

  • Gait velocity

    Walking speed across the room. Frailty, sarcopenia, and falls-risk signal.

  • Urinary cortisol

    Stress and HPA-axis signal.

  • Specific gravity

    Urine concentration. Direct hydration signal.

Sensors

  • ECG electrodes

    Contact electrodes integrated into the seat for short-arm and short-leg ECG. Captures rhythm, conduction, and waveform morphology each sit.

  • PPG / optical sensor

    Photoplethysmography optical sensors at the seat and handrail contact points. Captures heart rate, HRV, and SpO₂ from blood-volume pulse.

  • Mirror camera

    Low-resolution facial and torso imaging behind the mirror with on-device inference. Reads heart rate, respiration, and SpO₂ via remote photoplethysmography (rPPG); also captures skin tone, posture, and gesture. Raw frames never leave the room; only features.

  • Load cell array

    Strain-gauge load cells in the floor mat and seat for weight, weight distribution, balance, gait timing, and sit-to-stand dynamics.

  • Inertial sensors

    Accelerometer and gyroscope arrays for body sway during standing, gait acceleration profile, and falls detection in the room.

  • Urine immunoassay

    Lateral-flow and microfluidic assays measuring hormones, drug metabolites, and infection-specific biomarkers from urine.

  • Urinalysis test strip

    10-parameter reagent strip read at the seat. Captures pH, nitrites, leukocytes, glucose, blood, protein, ketones, urobilinogen, bilirubin, and specific gravity from each void.

  • Urine spectroscopy (optical / SERS)

    Non-contact optical analysis of urine in the bowl or stream. Uses vis-NIR absorbance, fluorescence, and surface-enhanced Raman spectroscopy (SERS) to fingerprint analytes without consumables. Calibrates against the same biochemistry strips read by urinalysis.

Open questions
  1. 01

    How might we read biological-age proxies without monthly bloodwork?

  2. 02

    How might we make age-trajectory legible to the cohort already paying for signal?

  3. 03

    How might we connect biological age to the rest of the bathroom record?

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